Definition of "occludin" [occludin]

• Any of a family of plasma-membrane protein located at tight junctions (noun)

Wiktionary.org : Text is available under the Creative Commons Attribution-ShareAlike License

• "By using a genetic screen, the group, led by Charles M. Rice, head of the Laboratory of Virology and Infectious Disease, identified a human protein, called occludin, that makes mouse cells susceptible to the virus."
• "Immunofluorescence studies revealed that hypoxia resulted in disrupted continuity of occludin and zonula occludens-1 (Zo-1) staining with significant gap formation."
• "Expression of claudin 4, claudin 18, and occludin was significantly lower, and activation of JNK and ERK signaling pathways was significantly increased in 2CLP monolayers, relative to sham monolayers."