Definition of "misfolded" [misfolded]

• Simple past tense and past participle of misfold. (verb)
• Folded into an incorrect tertiary structure (adjective)

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• "A protein with the wrong components, or that is misfolded, won't work as it is supposed to."
• "At the University of Chicago, Raymond Roos , a neurology professor and director of the ALS Clinic, is also studying how to clear misfolded proteins from the body."
• "Other researchers in the field say the finding is exciting, but further experiments are needed to show whether the misfolded ubiquilin 2 actually leads to a buildup of other toxic chemicals."