To ease or relieve (pain, for example).(verb-transitive)
To bring comfort, composure, or relief.(verb-intransitive)
American Heritage(R) Dictionary of the English Language, Fifth Edition. Copyright (c) 2011 by Houghton Mifflin Harcourt Publishing Company. Published by Houghton Mifflin Harcourt Publishing Company. All rights reserved.
Use "soothe" in a sentence
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"Little did you know but when I went back to school (after 30 years) Bramble Berry actually helped "soothe" my soul."
"At 7 months we did CIO after the non-sleeping, nurse in bed, rocking till our arms fell off, circus of trying to "soothe" an "energetic" boy."