Definition of "self-reactive" [self-reactive]

• Immunologically reactive to itself. Used of a cell or antibody. (adjective)

American Heritage(R) Dictionary of the English Language, Fifth Edition. Copyright (c) 2011 by Houghton Mifflin Harcourt Publishing Company. Published by Houghton Mifflin Harcourt Publishing Company. All rights reserved.

• "These self-reactive T cells stimulate other immune cells to produce autoantibodies that attach to the perfectly fine, healthy cells within our body—in any organ or tissue—and cause cells to die."
• "So far, early studies in MS populations are promising, indicating that Rituxan does lead to rapid depletion of self-reactive B cells."
• "Some of these are self-reactive (like on Elventh Hour, but without the picking up metals from their substrate part) in that they spread over the glass surface and bond with it."