Definition of "ornithine" [ornithine]

• An amino acid, C5H12N2O2, not found in proteins, formed by hydrolyzing arginine and important in the formation of urea. (noun)

American Heritage(R) Dictionary of the English Language, Fifth Edition. Copyright (c) 2011 by Houghton Mifflin Harcourt Publishing Company. Published by Houghton Mifflin Harcourt Publishing Company. All rights reserved.

• "DFMO is an inhibitor that specifically targets a key protein called ornithine decarboxylase"
• "The most common of the disorders is called ornithine transcarbamylase deficiency (OTC), with a prevalence of around one in 30,000, said Dr. Mark Batshaw, principal investigator of the Urea Cycle Disorders Consortium, part of the NIH's Office of Rare Diseases Research Network."
• "Such issues include Jesse Gelsinger20 suffered from a rare genetic disorder called ornithine transcarbamylase de fi - exotic therapies versus cheaper more widely ciency, which, while requiring cumbersome treat - useful therapies; ment with diet and drugs, was not a life-threatening disorder for him."