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Definition of "fibrinogen" [fi•brin•o•gen]

  • A protein in the blood plasma that is essential for the coagulation of blood and is converted to fibrin by the action of thrombin in the presence of ionized calcium. (noun)

American Heritage(R) Dictionary of the English Language, Fifth Edition. Copyright (c) 2011 by Houghton Mifflin Harcourt Publishing Company. Published by Houghton Mifflin Harcourt Publishing Company. All rights reserved.

Use "fibrinogen" in a sentence
  • "The Framingham study that has led to most of the theories about cholesterol levels and heart disease risk has now produced some interesting facts about another risk factor, the blood level of a blood-clotting factor called fibrinogen."
  • "A protein called fibrinogen that is known to help form blood clots also triggers scar formation in the brain and spinal cord, according to new research in the April 28 issue of the Journal of Neuroscience."
  • "Blood clot formation is usually initiated when damage to the inner lining of a blood vessel activates the "coagulation cascade," causing a blood protein called fibrinogen to crosslink into a fibrin clot."