Definition of "vorinostat" []

• A particular drug used to treat cancer. (noun)

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• "Paul Marks and Ronald Breslow at Columbia created a small molecule, called vorinostat, that blocks the action of the enzymes that tamper with DNA's packaging, thus turning inactivated genes back on."
• "The data in the publication in the British Journal of Cancer suggest that sapacitabine given in combination with HDAC inhibitors, such as vorinostat or sodium valproate, results in significantly enhanced cell death in AML cells and cell lines derived from other tumor tissues, including cutaneous T-cell lymphoma (CTCL), non-Hodgkins lymphoma (NHL) and non-small cell lung cancer (NSCLC)."
• "As a reference standard for the comparison of results, we used suberoylamide hydroxamic acid (SAHA; also referred to as "vorinostat"), a non-specific inhibitor of both classes of HDACs when used in the upper-nanomolar/micromolar range of concentrations [15]."