Definition of "vicriviroc" []

• A pyrimidine CCR5 entry inhibitor of HIV-1. (noun)

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• "Treatment-experienced patients from the vicriviroc clinical trials who are benefiting from vicriviroc treatment will continue to have access to the medicine as provided for in the trial protocols."
• "In the studies cited, HIV-infected patients whose virus was not well controlled were assigned to receive vicriviroc 30 mg once daily or placebo in combination with an optimized background regimen -- a regimen required to have at least two fully active antiretroviral drugs including a ritonavir-boosted protease inhibitor."
• "Joseph Gathe, MD, president of Therapeutic Concepts, Houston, who presented the results to a packed house during an oral abstract session here, said, "Optimized background therapy in these trials included more potent antiretroviral drugs than in the vicriviroc phase II clinical trials or in phase III trials of recently approved HIV drugs.""