- Of or relating to systems or a system. (adjective)
- Relating to or affecting the entire body or an entire organism: systemic symptoms; a systemic poison. (adjective)
- Relating to or affecting a particular body system, especially the nervous system: a systemic lesion. (adjective)
- Physiology Of or relating to systemic circulation. (adjective)
American Heritage(R) Dictionary of the English Language, Fifth Edition. Copyright (c) 2011 by Houghton Mifflin Harcourt Publishing Company. Published by Houghton Mifflin Harcourt Publishing Company. All rights reserved.