Definition of "rhabdomyolysis" [rhabdomyolysis]

• The rapid disintegration of striated muscle tissue accompanied by the excretion of myoglobin in the urine. (noun)

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• "Myopathy is marked by muscle pain and weakness, and in a serious form called rhabdomyolysis can damage the kidneys."
• "All of the statins have been linked with muscle injury and rare cases of muscle breakdown, a condition called rhabdomyolysis, which occurs in about five of every 100,000 patients taking cholesterol-lowering statin drugs."
• "Muscle pain and weakness, a condition called rhabdomyolysis, is actually the most common side effect of statin drugs, which is thought to occur because statins activate the atrogin-1 gene, which plays a key role in muscle atrophy. [xiii]"