Definition of "myelofibrosis" [myelofibrosis]

• Proliferation of fibroblastic cells in bone marrow, causing anemia and sometimes enlargement of the spleen and liver. (noun)

American Heritage(R) Dictionary of the English Language, Fifth Edition. Copyright (c) 2011 by Houghton Mifflin Harcourt Publishing Company. Published by Houghton Mifflin Harcourt Publishing Company. All rights reserved.

• "NEW ORLEANS ― A first-in-its class oral medication provides significant and durable relief for patients with a rare, debilitating and lethal bone marrow disorder called myelofibrosis, researchers at The University of Texas M."
• "Abstracts already released suggest that the studies are going to point to much bigger potential for '424 beyond its lead indication myelofibrosis, which is already viewed as a blockbuster opportunity."
• "*** Pharmaceuticals Novartis said an experimental drug for the treatment of myelofibrosis, a rare form of blood cancer, met the goals of a late-stage study, which should pave the way to file the drug for regulatory approval in the second quarter."