Definition of "isoxazole" []

• The isomer of oxazole 1,2-oxazole many of whose derivatives have pharmacological activity (noun)

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• "Leflunomide is an isoxazole immunomodulatory agent shown in animal studies to be both embryotoxic and teratogenic, and thus has been classified as pregnancy category X."
• "Applying SPR to the SeeDs method has successfully ascertained why isoxazole is a much more potent growth inhibitor than pyrazole, although they both have the same IC50 against Hsp90 (pyrazole is twofold faster on, but isoxazole is 15-fold slower off)."