Definition of "irritation" []

• The act of irritating. (noun)
• The condition of being irritated; vexation: honked the horn with irritation at the delay. (noun)
• A source of irritation. (noun)
• Pathology A condition of inflammation, soreness, or irritability of a bodily organ or part. (noun)
• Physiology The elicitation of activity or response in an animal or plant organ or tissue. (noun)

American Heritage(R) Dictionary of the English Language, Fifth Edition. Copyright (c) 2011 by Houghton Mifflin Harcourt Publishing Company. Published by Houghton Mifflin Harcourt Publishing Company. All rights reserved.

• "Where a woman is not allowed to show a certain irritation with such a question?"
• "And yet, whenever I ceased struggling for sleep, and lighted the lamp and read, my skin irritation decreased."
• ""Devil be damned!" was the next, uttered in irritation and anger."