- Any of several hereditary blood-coagulation disorders in which the blood fails to clot normally because of a deficiency or abnormality of one of the clotting factors. Hemophilia, a recessive trait associated with the X-chromosome, is manifested almost exclusively in males. (noun)
American Heritage(R) Dictionary of the English Language, Fifth Edition. Copyright (c) 2011 by Houghton Mifflin Harcourt Publishing Company. Published by Houghton Mifflin Harcourt Publishing Company. All rights reserved.