Definition of "glucokinase" [glucokinase]

• A hexokinase isozyme that facilitates phosphorylation of glucose to glucose-6-phosphate, occurring in cells in the liver, pancreas, gut, and brain of humans and most other vertebrates. (noun)

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• "GK HI is a rare type of HI caused by a defective glucokinase (GK) gene."
• "ZYGK1 acts by activating glucokinase, an enzyme that acts as a glucose sensor in the pancreas and regulates glucose metabolism in the liver."
• "Simultaneously, glucokinase activators increase the net uptake of blood glucose by the liver."