Definition of "deacetylase" [deacetylase]

• Any of several classes of enzyme that remove acetyl groups from proteins (noun)

Wiktionary.org : Text is available under the Creative Commons Attribution-ShareAlike License

• "Scientists then tested a class of drugs called histone deacetylase, or HDAC, inhibitors on the mice."
• "After exploring the biological mechanism behind the improvement in mice placed in the enriched environment, the researchers tested on the mice a class of drugs called histone deacetylase, or HDAC, inhibitors."
• "A group of agents called histone deacetylase inhibitors can help here, says Sharon Lewin, director of the infectious-diseases unit at Alfred Hospital in Melbourne, who is about to start a clinical trial of a histone-deacetylase inhibitor called SAHA."