The requirement of T cells for two signals in order to become fully activated(noun)
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Use "co-stimulation" in a sentence
"Food and Drug Administration´s (FDA) Cardiovascular and Renal Drugs Advisory Committee has voted 13 to 5 to recommend approval of belatacept, a selective co-stimulation blocker, for the prophylaxis of acute rejection in de novo kidney transplant patients."
"Macrophages were treated with noscapine or brominated noscapine analogs at 10, 25 and 50 µM prior to stimulation or co-stimulation with highly purified TLR-ligands (meningococcal LPS, a TLR4-MD-2 ligand and the synthetic lipopetide Pam3CSK4, a TLR2 ligand)."
"This study doesn't conclude that dual influence of IL-4 and TGF-β in presence of TCR stimulation and co-stimulation induces human"