A drug used to counteract the physiological effects of histamine production in allergic reactions and colds.(noun)
American Heritage(R) Dictionary of the English Language, Fifth Edition. Copyright (c) 2011 by Houghton Mifflin Harcourt Publishing Company. Published by Houghton Mifflin Harcourt Publishing Company. All rights reserved.
Use "antihistamine" in a sentence
"Partly because of that inconvenience, the shots are generally recommended only when other strategies, such as antihistamine drugs or dust-mite covers on mattresses, bedding, and sofas, have failed to adequately control symptoms."
"The doctors gave me a prescription for some kind of antihistamine that I should take all the time, told me to stay away from nuts because even though the tests were inconclusive, they still kinda thought that maybe somehow nuts were involved maybe or something."
"This may not seem odd because of the fact that it is an allergy medicine, and is an antihistamine which is notorious for causing drowsiness, but I have been taking Zyrtec every allergy season for the past four years now."