The formation of vacuoles in a cellular tissue (noun)
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Use "vacuolation" in a sentence
"The morbid changes consist of an inflammation of the papillary region of the derma, leading to [oe] dema and vacuolation of the constituent cells of the epidermis, followed by their complete destruction in places and their abnormal proliferation in others (Fordyce)."
"Brominated noscapine analogs when added to macrophages significantly induced autophagy as evident by extensive autophagy-related vacuolation in cytoplasm and upregulation of microtubule-associated light-chain protein,"
"Drug induced autophagy was noted with increased vacuolation in the cytoplasm."